June 13, 2017

Agarwood (Aquilaria) leaves have been consumed as a beverage for health promotion in many countries. In the past few years, Aquilaria Crassna leaves have been studied further due to their potential in antioxidative, antibacterial, antipyretic, analgesic, and laxative activities ( for past research click here)Supasuteekul (et al 2016)'s and his team research show that these leaves are the sources of neuritogenic and neuroprotective constituents, which may be processed as a natural supplement or functional foods for neurodegenerative disorder prevention such as age related chronic diseases: : Alzheimer’s disease and Parkinson’s disease

The above table is the lab test result of our agarwood leaves which have the same compounds in this study by Supasuteekul, Tadtong, Putalun, Tanaka, Likhiwitayawuid, Tengamnuay and Sritularak (2016, Journal of Food Biochemistry)

Chromatographic separation from Aquilaria Crassna's leaves led to the isolation of three phenolic glycosides

1) genkwanin 5-O-β-primevoside
2) iriflophenone 3,5-C-β-D-diglucoside

3) iriflophenone 3-C-β-D-glucoside

Compounds 1 and 2 were shwon to be the active principles responsible for the neuroprotective and neuritogenic of Aquilaria Crassna. However, their exact mechanism of neuroprection still need further investigation.

 

 

 

 


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